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bioss bs 2464r  (Bioss)


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    Bioss bioss bs 2464r
    Abcam ab64186 recognizes NRN1 protein in rat primary neurons and mouse brain. (A) Representative Western blot of rat primary cortical (CTX) and hippocampal (HPC) neuron lysates (50 µg protein), probed with NRN1 polyclonal antibody Invitrogen PA5‐47406. (B) Representative Western blot of rat primary CTX and HPC neuron lysates, probed with NRN1 polyclonal antibody Bioss <t>bs‐2464R.</t> (C) Representative Western blot of rat primary CTX and HPC neuron lysates, probed with NRN1 polyclonal antibody Abcam ab64186. (D) Densitometry analysis of panel (C) reveals that when normalized to GAPDH, the observed protein levels of NRN1 are comparable in rat CTX or HPC primary neuron cultures ( t [4] = 0.9868, p = 0.3796). Unpaired t ‐tests were used for comparisons. (E) Representative Western blot of WT C57BL/6N mice lysate (50 µg protein), probed with NRN1 polyclonal antibody Abcam ab64186. (F) Densitometry analysis of panel (E) reveals that when normalized to GAPDH, the observed protein levels of NRN1 in WT C57BL/6N mice are equivalent in the prelimbic mPFC and hippocampus (HPC) t (6 = 0.8453, p = 0.4304). Unpaired two‐tailed t ‐tests were used for comparisons. Each point represents one mouse. N = 4 mice (2 male, 2 female). Error bars represent the standard deviation of the mean. a.u. = arbitrary units. GAPDH, glyceraldehyde‐3‐phosphate dehydrogenase; mPFC, medial prefrontal cortex; NRN1, Neuritin‐1; WT, wild type.
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    1) Product Images from "NRN1 as a therapeutic target for Alzheimer's disease"

    Article Title: NRN1 as a therapeutic target for Alzheimer's disease

    Journal: Alzheimer's & Dementia

    doi: 10.1002/alz.71149

    Abcam ab64186 recognizes NRN1 protein in rat primary neurons and mouse brain. (A) Representative Western blot of rat primary cortical (CTX) and hippocampal (HPC) neuron lysates (50 µg protein), probed with NRN1 polyclonal antibody Invitrogen PA5‐47406. (B) Representative Western blot of rat primary CTX and HPC neuron lysates, probed with NRN1 polyclonal antibody Bioss bs‐2464R. (C) Representative Western blot of rat primary CTX and HPC neuron lysates, probed with NRN1 polyclonal antibody Abcam ab64186. (D) Densitometry analysis of panel (C) reveals that when normalized to GAPDH, the observed protein levels of NRN1 are comparable in rat CTX or HPC primary neuron cultures ( t [4] = 0.9868, p = 0.3796). Unpaired t ‐tests were used for comparisons. (E) Representative Western blot of WT C57BL/6N mice lysate (50 µg protein), probed with NRN1 polyclonal antibody Abcam ab64186. (F) Densitometry analysis of panel (E) reveals that when normalized to GAPDH, the observed protein levels of NRN1 in WT C57BL/6N mice are equivalent in the prelimbic mPFC and hippocampus (HPC) t (6 = 0.8453, p = 0.4304). Unpaired two‐tailed t ‐tests were used for comparisons. Each point represents one mouse. N = 4 mice (2 male, 2 female). Error bars represent the standard deviation of the mean. a.u. = arbitrary units. GAPDH, glyceraldehyde‐3‐phosphate dehydrogenase; mPFC, medial prefrontal cortex; NRN1, Neuritin‐1; WT, wild type.
    Figure Legend Snippet: Abcam ab64186 recognizes NRN1 protein in rat primary neurons and mouse brain. (A) Representative Western blot of rat primary cortical (CTX) and hippocampal (HPC) neuron lysates (50 µg protein), probed with NRN1 polyclonal antibody Invitrogen PA5‐47406. (B) Representative Western blot of rat primary CTX and HPC neuron lysates, probed with NRN1 polyclonal antibody Bioss bs‐2464R. (C) Representative Western blot of rat primary CTX and HPC neuron lysates, probed with NRN1 polyclonal antibody Abcam ab64186. (D) Densitometry analysis of panel (C) reveals that when normalized to GAPDH, the observed protein levels of NRN1 are comparable in rat CTX or HPC primary neuron cultures ( t [4] = 0.9868, p = 0.3796). Unpaired t ‐tests were used for comparisons. (E) Representative Western blot of WT C57BL/6N mice lysate (50 µg protein), probed with NRN1 polyclonal antibody Abcam ab64186. (F) Densitometry analysis of panel (E) reveals that when normalized to GAPDH, the observed protein levels of NRN1 in WT C57BL/6N mice are equivalent in the prelimbic mPFC and hippocampus (HPC) t (6 = 0.8453, p = 0.4304). Unpaired two‐tailed t ‐tests were used for comparisons. Each point represents one mouse. N = 4 mice (2 male, 2 female). Error bars represent the standard deviation of the mean. a.u. = arbitrary units. GAPDH, glyceraldehyde‐3‐phosphate dehydrogenase; mPFC, medial prefrontal cortex; NRN1, Neuritin‐1; WT, wild type.

    Techniques Used: Western Blot, Two Tailed Test, Standard Deviation



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    Abcam ab64186 recognizes NRN1 protein in rat primary neurons and mouse brain. (A) Representative Western blot of rat primary cortical (CTX) and hippocampal (HPC) neuron lysates (50 µg protein), probed with NRN1 polyclonal antibody Invitrogen PA5‐47406. (B) Representative Western blot of rat primary CTX and HPC neuron lysates, probed with NRN1 polyclonal antibody Bioss <t>bs‐2464R.</t> (C) Representative Western blot of rat primary CTX and HPC neuron lysates, probed with NRN1 polyclonal antibody Abcam ab64186. (D) Densitometry analysis of panel (C) reveals that when normalized to GAPDH, the observed protein levels of NRN1 are comparable in rat CTX or HPC primary neuron cultures ( t [4] = 0.9868, p = 0.3796). Unpaired t ‐tests were used for comparisons. (E) Representative Western blot of WT C57BL/6N mice lysate (50 µg protein), probed with NRN1 polyclonal antibody Abcam ab64186. (F) Densitometry analysis of panel (E) reveals that when normalized to GAPDH, the observed protein levels of NRN1 in WT C57BL/6N mice are equivalent in the prelimbic mPFC and hippocampus (HPC) t (6 = 0.8453, p = 0.4304). Unpaired two‐tailed t ‐tests were used for comparisons. Each point represents one mouse. N = 4 mice (2 male, 2 female). Error bars represent the standard deviation of the mean. a.u. = arbitrary units. GAPDH, glyceraldehyde‐3‐phosphate dehydrogenase; mPFC, medial prefrontal cortex; NRN1, Neuritin‐1; WT, wild type.
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    Abcam ab64186 recognizes NRN1 protein in rat primary neurons and mouse brain. (A) Representative Western blot of rat primary cortical (CTX) and hippocampal (HPC) neuron lysates (50 µg protein), probed with NRN1 polyclonal antibody Invitrogen PA5‐47406. (B) Representative Western blot of rat primary CTX and HPC neuron lysates, probed with NRN1 polyclonal antibody Bioss <t>bs‐2464R.</t> (C) Representative Western blot of rat primary CTX and HPC neuron lysates, probed with NRN1 polyclonal antibody Abcam ab64186. (D) Densitometry analysis of panel (C) reveals that when normalized to GAPDH, the observed protein levels of NRN1 are comparable in rat CTX or HPC primary neuron cultures ( t [4] = 0.9868, p = 0.3796). Unpaired t ‐tests were used for comparisons. (E) Representative Western blot of WT C57BL/6N mice lysate (50 µg protein), probed with NRN1 polyclonal antibody Abcam ab64186. (F) Densitometry analysis of panel (E) reveals that when normalized to GAPDH, the observed protein levels of NRN1 in WT C57BL/6N mice are equivalent in the prelimbic mPFC and hippocampus (HPC) t (6 = 0.8453, p = 0.4304). Unpaired two‐tailed t ‐tests were used for comparisons. Each point represents one mouse. N = 4 mice (2 male, 2 female). Error bars represent the standard deviation of the mean. a.u. = arbitrary units. GAPDH, glyceraldehyde‐3‐phosphate dehydrogenase; mPFC, medial prefrontal cortex; NRN1, Neuritin‐1; WT, wild type.
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    Image Search Results


    Abcam ab64186 recognizes NRN1 protein in rat primary neurons and mouse brain. (A) Representative Western blot of rat primary cortical (CTX) and hippocampal (HPC) neuron lysates (50 µg protein), probed with NRN1 polyclonal antibody Invitrogen PA5‐47406. (B) Representative Western blot of rat primary CTX and HPC neuron lysates, probed with NRN1 polyclonal antibody Bioss bs‐2464R. (C) Representative Western blot of rat primary CTX and HPC neuron lysates, probed with NRN1 polyclonal antibody Abcam ab64186. (D) Densitometry analysis of panel (C) reveals that when normalized to GAPDH, the observed protein levels of NRN1 are comparable in rat CTX or HPC primary neuron cultures ( t [4] = 0.9868, p = 0.3796). Unpaired t ‐tests were used for comparisons. (E) Representative Western blot of WT C57BL/6N mice lysate (50 µg protein), probed with NRN1 polyclonal antibody Abcam ab64186. (F) Densitometry analysis of panel (E) reveals that when normalized to GAPDH, the observed protein levels of NRN1 in WT C57BL/6N mice are equivalent in the prelimbic mPFC and hippocampus (HPC) t (6 = 0.8453, p = 0.4304). Unpaired two‐tailed t ‐tests were used for comparisons. Each point represents one mouse. N = 4 mice (2 male, 2 female). Error bars represent the standard deviation of the mean. a.u. = arbitrary units. GAPDH, glyceraldehyde‐3‐phosphate dehydrogenase; mPFC, medial prefrontal cortex; NRN1, Neuritin‐1; WT, wild type.

    Journal: Alzheimer's & Dementia

    Article Title: NRN1 as a therapeutic target for Alzheimer's disease

    doi: 10.1002/alz.71149

    Figure Lengend Snippet: Abcam ab64186 recognizes NRN1 protein in rat primary neurons and mouse brain. (A) Representative Western blot of rat primary cortical (CTX) and hippocampal (HPC) neuron lysates (50 µg protein), probed with NRN1 polyclonal antibody Invitrogen PA5‐47406. (B) Representative Western blot of rat primary CTX and HPC neuron lysates, probed with NRN1 polyclonal antibody Bioss bs‐2464R. (C) Representative Western blot of rat primary CTX and HPC neuron lysates, probed with NRN1 polyclonal antibody Abcam ab64186. (D) Densitometry analysis of panel (C) reveals that when normalized to GAPDH, the observed protein levels of NRN1 are comparable in rat CTX or HPC primary neuron cultures ( t [4] = 0.9868, p = 0.3796). Unpaired t ‐tests were used for comparisons. (E) Representative Western blot of WT C57BL/6N mice lysate (50 µg protein), probed with NRN1 polyclonal antibody Abcam ab64186. (F) Densitometry analysis of panel (E) reveals that when normalized to GAPDH, the observed protein levels of NRN1 in WT C57BL/6N mice are equivalent in the prelimbic mPFC and hippocampus (HPC) t (6 = 0.8453, p = 0.4304). Unpaired two‐tailed t ‐tests were used for comparisons. Each point represents one mouse. N = 4 mice (2 male, 2 female). Error bars represent the standard deviation of the mean. a.u. = arbitrary units. GAPDH, glyceraldehyde‐3‐phosphate dehydrogenase; mPFC, medial prefrontal cortex; NRN1, Neuritin‐1; WT, wild type.

    Article Snippet: Herein, we compared three commercially available polyclonal (pAb) NRN1 antibodies: Abcam ab64186, Bioss bs‐2464R, and Invitrogen PA5‐47406.

    Techniques: Western Blot, Two Tailed Test, Standard Deviation